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Phenotypes Associated with This Genotype
Genotype
MGI:5491456
Allelic
Composition		 Gt(ROSA)26Sortm1(Kdm6b)Scla/Gt(ROSA)26Sor+
Kdm6bGt(XB814)Byg/Kdm6bGt(XB814)Byg
Tg(Pgk1-cre)1Lni/0
Genetic
Background		 involves: 129P2/OlaHsd * BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(Kdm6b)Scla mutation (0 available); any Gt(ROSA)26Sor mutation (1026 available)
Kdm6bGt(XB814)Byg mutation (0 available); any Kdm6b mutation (67 available)
Tg(Pgk1-cre)1Lni mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:196346 )
N
• neonatal lethality observed in Kdm6bGt(XB814)Byg homozygotes is rescued

nervous system
nervous system phenotype ( J:196346 )
N
• mice exhibit normal pre-Botzinger complex

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory