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Phenotypes Associated with This Genotype
Genotype
MGI:5496535
Allelic
Composition		 Ceacam1tm1.1Fta/Ceacam1tm1.1Fta
Genetic
Background		 C57BL/6(FVB)-Ceacam1tm1.1Fta
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ceacam1tm1.1Fta mutation (0 available); any Ceacam1 mutation (45 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
decreased susceptibility to Coronaviridae infection induced morbidity/mortality ( J:198335 )
• mice are resistant to mouse hepatitis virus (MHV) infection unlike C57BL/6 controls but similar to SJL mice

immune system
decreased susceptibility to Coronaviridae infection ( J:198335 )
• infection with mouse hepatitis virus (MHV A59) infection are fully resistant to lethality and viral accumulation observed in C57BL/6 control mice
• MHV fails to replicate in peritoneal macrophages
decreased susceptibility to Coronaviridae infection induced morbidity/mortality ( J:198335 )
• mice are resistant to mouse hepatitis virus (MHV) infection unlike C57BL/6 controls but similar to SJL mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory