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Phenotypes Associated with This Genotype
Genotype
MGI:5501493
Allelic
Composition		 Nfkbiztm1.1Muta/Nfkbiztm1.1Muta
Tg(KRT5-cre)1Tak/?
Genetic
Background		 involves: C3H * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nfkbiztm1.1Muta mutation (1 available); any Nfkbiz mutation (33 available)
Tg(KRT5-cre)1Tak mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
dermatitis ( J:194832 )
• inflammation present

vision/eye
increased lacrimal gland apoptosis ( J:194832 )
• increased apoptosis

integument
dermatitis ( J:194832 )
• inflammation present

endocrine/exocrine glands
increased lacrimal gland apoptosis ( J:194832 )
• increased apoptosis

cellular
increased lacrimal gland apoptosis ( J:194832 )
• increased apoptosis

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory