Phenotypes Associated with This Genotype

Genotype
MGI:5503123

• Allelic Composition: Kif13a^tm1.1Noh/Kif13a^tm1.1Noh
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:196383 )

N • mice exhibit normal performance on a rotarod

increased anxiety-related response ( J:196383 )

• in an open field, mice spend less time in the center or crossing the center compared with wild-type mice

• in an elevated-plus maze, mice spend less time in open arms and enter open arms less than wild-type mice

increased thigmotaxis ( J:196383 )

• in an open field, mice spend less time in the center or crossing the center compared with wild-type mice

decreased locomotor activity ( J:196383 )

• in an open field

homeostasis/metabolism

decreased physiological sensitivity to xenobiotic ( J:196383 )

• mice treated with WAY-100635 fail to exhibit a decrease in time spent in the center of an open field unlike wild-type mice