Phenotypes Associated with This Genotype

Genotype
MGI:5503968

• Allelic Composition: Fbxl3^tm1Kei/Fbxl3^tm1Kei
• Genetic Background: B6.129P2-Fbxl3^tm1Kei

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

prolonged circadian behavior period ( J:196293 )

• when mice are kept in constant darkness, free-running period is increased compared to in wild-type mice

abnormal circardian behavior entrainment ( J:196293 )

• when mice are entrained to a 12L:12D cycle (LD), the onset of active phase is delayed from the light-to-dark transition compared to in wild-type mice

• when transferred from constant darkness (DD) to LD, mice fail to entrain and free run as in DD