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Phenotypes Associated with This Genotype
Genotype
MGI:5506525
Allelic
Composition
Etv1tm1Tmj/Etv1tm2Tmj
Tg(EGR3-WGA)1Tmj/0
Genetic
Background
involves: 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Etv1tm1Tmj mutation (0 available); any Etv1 mutation (44 available)
Etv1tm2Tmj mutation (0 available); any Etv1 mutation (44 available)
Tg(EGR3-WGA)1Tmj mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
muscle
• mutants exhibit loss of about 65% of WGA-positive muscle spindles relative to controls

nervous system
• mutants exhibit loss of about 65% of WGA-positive muscle spindles relative to controls
• number of wheat germ agglutinin-positive (WGA) proprioceptive sensory neurons in L2 and L5 DRG is significantly reduced (to 20% of control)


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory