Phenotypes Associated with This Genotype

Genotype
MGI:5523594

• Allelic Composition: Gli3^tm1.2Zllr/Gli3⁺; Pkdcc^tm1.2Azun/Pkdcc^tm1.2Azun
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

decreased length of long bones ( J:199462 )

• shorter ossified section at birth

• more severe than in mice homozygous for the Pkdcc mutation alone

short humerus ( J:199462 )

• tibia and humerus are most severely affected

short tibia ( J:199462 )

• tibia and humerus are most severely affected

abnormal scapula morphology ( J:199462 )

• deformed in some mice at E16.5

delayed endochondral bone ossification ( J:199462 )

• in long bones

• more severe than in mice homozygous for the Pkdcc mutation alone

limbs/digits/tail

short humerus ( J:199462 )

• tibia and humerus are most severely affected

short tibia ( J:199462 )

• tibia and humerus are most severely affected