Phenotypes Associated with This Genotype

Genotype
MGI:5524260

• Allelic Composition: Tg(Thy1-Nrg1*I)1Kan/0
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

muscle

abnormal muscle spindle morphology ( J:199150 )

• large diameter and high intrafusal fiber numbers

• however, outer capsule morphology and innervation

increased muscle spindle number ( J:199150 )

• in newborn mice persisting through adulthood

nervous system

abnormal muscle spindle morphology ( J:199150 )

• large diameter and high intrafusal fiber numbers

• however, outer capsule morphology and innervation

increased muscle spindle number ( J:199150 )

• in newborn mice persisting through adulthood

abnormal proprioceptive neuron morphology ( J:199150 )

• mice exhibit increased survival of proprioceptive neurons during the selection phase compared with wild-type mice