Phenotypes Associated with This Genotype

Genotype
MGI:5527435

• Allelic Composition: Gt(ROSA)26Sor^{tm1(CAG-Etv2,-GFP)Hkata}/Gt(ROSA)26Sor⁺; Commd10^{Tg(Vav1-icre)A2Kio}/Commd10⁺
• Genetic Background: involves: C57BL/6NCrlj * C57BL/10 * CBA/Ca * CBA/JNCrlj

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:203163 )

• fewer than expected mice are observed at P10

hematopoietic system

abnormal hematopoietic system morphology/development ( J:203163 )

• disturbed hematopoietic development in adult hematopoietic progenitor cells

anemia ( J:203163 )

• severe in some mice

abnormal bone marrow cell morphology/development ( J:203163 )

• reduced total number of colony forming units from bone marrow cells

decreased common myeloid progenitor cell number ( J:203163 )

• in bone marrow cells

decreased erythroid progenitor cell number ( J:203163 )

• in bone marrow cells