Phenotypes for Wfikkn1 Wfikkn2 MGI:5546332 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Wfikkn1^tm1.1Sjl/Wfikkn1^tm1.1Sjl Wfikkn2^tm1.1Sjl/Wfikkn2^tm1.1Sjl
Genetic Background	involves: 129 * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Wfikkn1^tm1.1Sjl mutation (0 available); any Wfikkn1 mutation (15 available)
Wfikkn2^tm1.1Sjl mutation (0 available); any Wfikkn2 mutation (20 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Impaired muscle regeneration in Wfikkn2^tm1.1Sjl/Wfikkn2^tm1.1Sjl, Wfikkn1^tm1.1Sjl/Wfikkn1^tm1.1Sjl, and double mutant mice after cardiotoxin injury

muscle

impaired skeletal muscle regeneration ( J:201148 )

• impaired regeneration following cardiotoxin induced injury of the gastrocnemius muscle

skeleton

abnormal axial skeleton morphology ( J:201148 )

• patterning defects are similar to mice homozygous for Wfikkn1^tm1.1Sjl alone

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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