Phenotypes Associated with This Genotype

Genotype
MGI:5546511

• Allelic Composition: Trpm7^tm1Agry/Trpm7^tm1Agry
• Genetic Background: involves: 129

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

prenatal lethality, complete penetrance ( J:205665 )

• no mice are born

embryo

embryonic growth arrest ( J:205665 )

• arrest after a full day of gastrulation

decreased embryo size ( J:205665 )

• at E7.5

cellular

abnormal cell physiology ( J:205665 )

• ES cells do not grow significantly in control media

• however, supplemental magnesium rescues growth

growth/size/body

decreased embryo size ( J:205665 )

• at E7.5