mortality/aging
• mice that survive beyond birth die by P22
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• few mice survive beyond birth
|
respiratory system
N |
• mice exhibit normal surfactant and mucous
|
• with increased neutrophils as early as P14 in mice that survive to P22
|
• necrosis of alveolar epithelium in mice that survive to P22
|
• collapsed alveolar space at E18.5
|
• in most mice delivered by caesarian section
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homeostasis/metabolism
immune system
• in the lungs of mice that survive to P22
|
• with increased neutrophils as early as P14 in mice that survive to P22
|
hematopoietic system
• in the lungs of mice that survive to P22
|