Phenotypes Associated with This Genotype

Genotype
MGI:5551787

• Allelic Composition: Washc1^tm1.1Xya/Washc1^tm1.1Xya
• Genetic Background: involves: 129 * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality, complete penetrance ( J:202483 )

• mice die and are resorbed at E9.5

embryo

abnormal embryo development ( J:202483 )

• at E7.5, mice lack endoderm, mesoderm and ectoderm

abnormal amniotic cavity morphology ( J:202483 )

• not well organized

abnormal ectoplacental cavity morphology ( J:202483 )

• not well organized

abnormal extraembryonic coelom morphology ( J:202483 )

• not well organized

cellular

abnormal autophagy ( J:202483 )

• autophagic phenotype in E7.5 embryos

increased cell death ( J:202483 )

• autophagic phenotype in E7.5 embryos

homeostasis/metabolism

abnormal autophagy ( J:202483 )

• autophagic phenotype in E7.5 embryos