Phenotypes for Commd10 Ifngr1 MGI:5558063 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ifngr1^tm1.1Rds/Ifngr1^tm1.1Rds Commd10^{Tg(Vav1-icre)A2Kio}/Commd10⁺
Genetic Background	B6NTac.Cg-Ifngr1^tm1.1Rds Commd10^{Tg(Vav1-icre)A2Kio}

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Commd10^{Tg(Vav1-icre)A2Kio} mutation (4 available); any Commd10 mutation (25 available)
Ifngr1^tm1.1Rds mutation (1 available); any Ifngr1 mutation (53 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

increased susceptibility to bacterial infection induced morbidity/mortality ( J:206257 )

• in mice infected with L. monocytogenes

immune system

increased susceptibility to bacterial infection ( J:206257 )

• mice infected with L. monocytogenes exhibit increased mortality and spleen and liver bacterial counts compared with control mice

increased susceptibility to bacterial infection induced morbidity/mortality ( J:206257 )

• in mice infected with L. monocytogenes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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