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Phenotypes Associated with This Genotype
Genotype
MGI:5560659
Allelic
Composition		 Mef2atm1.1Limm/Mef2atm1.1Limm
Mef2dtm3Eno/Mef2dtm3Eno
Tg(GFAP-cre)25Mes/0
Genetic
Background		 involves: 129S/SvEv * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mef2atm1.1Limm mutation (0 available); any Mef2a mutation (36 available)
Mef2dtm3Eno mutation (0 available); any Mef2d mutation (66 available)
Tg(GFAP-cre)25Mes mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:207812 )
N
• mice exhibit normal learning and memory in context- and cue-dependent fear conditioning tests, normal anxiety-related behaviors and pain sensitivity
impaired coordination ( J:207812 )
• on a rotarod

nervous system
nervous system phenotype ( J:207812 )
N
• mice exhibit normal synapse number and basal synaptic transmission

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory