Phenotypes Associated with This Genotype

Genotype
MGI:5561370

• Allelic Composition: Tll1^b2b2476Clo/Tll1^b2b2476Clo
• Genetic Background: C57BL/6J-Tll1^b2b2476Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Mutant 2476-007-1 (E16.5) is developmentally delayed, exhibits parallel outflow tracts and thin ventricle walls which is diagnosed as DORV and ventricular non-compaction by EFIC imaging

cardiovascular system

abnormal myocardium compact layer morphology ( J:175213 )

• Excessive myocardial trabeculation or noncompaction

double outlet right ventricle ( J:175213 )

overriding aortic valve ( J:175213 )

ventricular septal defect ( J:175213 )

perimembraneous ventricular septal defect ( J:175213 )

muscular ventricular septal defect ( J:175213 )

craniofacial

abnormal palate morphology ( J:175213 )

digestive/alimentary system

abnormal palate morphology ( J:175213 )

hematopoietic system

thymus hypoplasia ( J:175213 )

immune system

thymus hypoplasia ( J:175213 )

endocrine/exocrine glands

thymus hypoplasia ( J:175213 )

growth/size/body

abnormal palate morphology ( J:175213 )

muscle

abnormal myocardium compact layer morphology ( J:175213 )

• Excessive myocardial trabeculation or noncompaction