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Phenotypes Associated with This Genotype
Genotype
MGI:5563102
Allelic
Composition
Itchtm1.1Alta/Itchtm1.1Alta
Gt(ROSA)26Sortm1Hjf/Gt(ROSA)26Sor+
Foxp3tm4(YFP/icre)Ayr/Foxp3+
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxp3tm4(YFP/icre)Ayr mutation (2 available); any Foxp3 mutation (57 available)
Gt(ROSA)26Sortm1Hjf mutation (5 available); any Gt(ROSA)26Sor mutation (997 available)
Itchtm1.1Alta mutation (0 available); any Itch mutation (92 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
N
• regulatory T cells exhibit normal suppressive functions and stability


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory