Phenotypes Associated with This Genotype

Genotype
MGI:5563352

• Allelic Composition: Cd72^c/Cd72^c
• Genetic Background: involves: C57BL/6 * MRL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

immune system phenotype ( J:204782 )

N • mice exhibit normal spleen weight and percentage of B cells and T cells in the spleen as compared with C57BL/6 mice

increased B cell proliferation ( J:204782 )

• in spleen B cells stimulated with CpG oligomers or anti-CD40 antibodies compared with cells from C57BL/6 mice

• however, proliferation in response to anti-IgM stimulation is normal

hematopoietic system

increased B cell proliferation ( J:204782 )

• in spleen B cells stimulated with CpG oligomers or anti-CD40 antibodies compared with cells from C57BL/6 mice

• however, proliferation in response to anti-IgM stimulation is normal

cellular

increased B cell proliferation ( J:204782 )

• in spleen B cells stimulated with CpG oligomers or anti-CD40 antibodies compared with cells from C57BL/6 mice

• however, proliferation in response to anti-IgM stimulation is normal