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Phenotypes Associated with This Genotype
Genotype
MGI:5568088
Allelic
Composition
Npr2tm2.1(cre/ERT2)Fgr/Npr2cn
Tg(CAG-Bgeo/ALPP)1Lbe/0
Genetic
Background
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * AKR/J * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Npr2cn mutation (2 available); any Npr2 mutation (63 available)
Npr2tm2.1(cre/ERT2)Fgr mutation (0 available); any Npr2 mutation (63 available)
Tg(CAG-Bgeo/ALPP)1Lbe mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
N
• at E15.5 formation of collaterals by cranial sensory axons is not affected by Npr2 deficiency
• peripheral processes of the ophthalmic branch of the trigeminal nerve are not significantly affected by Npr2 deficiency
• at E12.5 axons from cranial sensory ganglia do not bifurcate at the entry zone to the brainstem
• mice lack axon bifurcation of DRG neurons; axons only exhibit only turns with Npr2 deficiency


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory