About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5573158
Allelic
Composition		 Tg(Cnp-MAPT*P301L)6Vle/0
Tg(Cnp-SNCA)M2Vle/0
Genetic
Background		 involves: C3H * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Cnp-MAPT*P301L)6Vle mutation (0 available)
Tg(Cnp-SNCA)M2Vle mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
jerky movement ( J:127923 )
• limb-twitch phenotype

nervous system
tau protein deposits ( J:127923 )
• mice exhibit accumulation of tau and alpha-synuclein amyloidogenic inclusions in oligodendrocytes as early as 12 months of age
alpha-synuclein inclusion body ( J:127923 )
• mice exhibit accumulation of tau and alpha-synuclein amyloidogenic inclusions in oligodendrocytes as early as 12 months of age

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory