Phenotypes Associated with This Genotype

Genotype
MGI:5575561

• Allelic Composition: Raph1^tm1.1Makr/Raph1^tm1.1Makr; Tg(Pgk1-cre)1Lni/0
• Genetic Background: involves: BALB/c * C57BL/6 * C57BL/6NTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, incomplete penetrance ( J:208191 )

• Background Sensitivity: mice on a pure C57BL/6 genetic background (details not specified) tend to die shortly after birth unlike mice on a mixed background that are present in Mendelian ratios at P0

postnatal lethality, incomplete penetrance ( J:208191 )

• Background Sensitivity: fewer than expected mice on a mixed background are alive at P10 with many mice dying before 6 weeks of age

reproductive system

infertility ( J:208191 )

• Background Sensitivity: mice on a mixed background that reach sexual maturity are infertile

growth/size/body

decreased body size ( J:208191 )

pigmentation

belly spot ( J:208191 )

behavior/neurological

absent gastric milk in neonates ( J:208191 )

integument

belly spot ( J:208191 )