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Phenotypes Associated with This Genotype
Genotype
MGI:5576974
Allelic
Composition
Hprt1tm4(CAG-Tbx18*,-Venus)Akis/Y
Tbx18tm4(cre)Akis/Tbx18+
Genetic
Background
involves: 129S1/SvImJ * NMRI
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hprt1tm4(CAG-Tbx18*,-Venus)Akis mutation (0 available); any Hprt1 mutation (1281 available)
Tbx18tm4(cre)Akis mutation (0 available); any Tbx18 mutation (36 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging

cardiovascular system
N
• cardiomyocytes apoptosis and size are normal
• sinus horn defects
• beginning at E12.5 and worsening at E14.5
• in the right ventricular myocardium at E12.5 and E13.5

cellular
• in the right ventricular myocardium at E12.5 and E13.5

muscle
• beginning at E12.5 and worsening at E14.5
• in the right ventricular myocardium at E12.5 and E13.5


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory