Phenotypes for Ctnnb1 Tg(Tek-cre)1Ywa MGI:5581949 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ctnnb1^tm2Kem/Ctnnb1^tm2Kem Tg(Tek-cre)1Ywa/0
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ctnnb1^tm2Kem mutation (1 available); any Ctnnb1 mutation (49 available)
Tg(Tek-cre)1Ywa mutation (6 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

prenatal lethality, incomplete penetrance ( J:178340 )

• fewer than expected mice are born

skeleton

decreased osteoclast cell number ( J:178340 )

increased bone volume ( J:178340 )

osteopetrosis ( J:178340 )

decreased bone resorption ( J:178340 )

hematopoietic system

decreased osteoclast cell number ( J:178340 )

immune system

decreased osteoclast cell number ( J:178340 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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