Analysis Tools
reproductive system
 N |
• ovary weight and oocyte apoptosis are normal
|
azoospermia
(
J:213984
)
 |
|
|
• non-homologous chromosome synapsis in spermatocytes and oocytes
|
|
|
• most chromosomes are univalent with few bivalent resulting in aneuloidy
|
|
|
• few or partial synapsis are observed and some
|
|
|
• absence of diplotene stage spermatocytes due to apoptosis
|
|
|
• absence of diplotene stage spermatocytes due to apoptosis
|
|
|
• one third of wild-type
|
cellular
azoospermia
(
J:213984
)
|
|
|
aneuploidy
(
J:213984
)
|
|
• in oocyte
|
|
• non-homologous chromosome synapsis in spermatocytes and oocytes
|
|
|
• most chromosomes are univalent with few bivalent resulting in aneuloidy
|
|
|
• few or partial synapsis are observed and some
|
|
|
• absence of diplotene stage spermatocytes due to apoptosis
|
|
|
• absence of diplotene stage spermatocytes due to apoptosis
|
|
|
• decreased or absent double strand DNA break formation in spermatocytes
|
|
|
• no embryos are observed at implantation sites due to aneuploidy
• however, some oocytes are capable of fertilization and implantation
|
endocrine/exocrine glands
|
|
• one third of wild-type
|
homeostasis/metabolism
|
|
• decreased or absent double strand DNA break formation in spermatocytes
|
