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Phenotypes Associated with This Genotype
Genotype
MGI:5605479
Allelic
Composition		 Ryr2tm1.1Swch/Ryr2tm2.1Swch
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * Black Swiss
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ryr2tm1.1Swch mutation (0 available); any Ryr2 mutation (325 available)
Ryr2tm2.1Swch mutation (0 available); any Ryr2 mutation (325 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal cardiovascular system physiology ( J:214434 )
• mice are resistant to catecholaminergic polymorphic ventricular tachycardia induced by the administration of caffeine and epinephrine

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory