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Phenotypes Associated with This Genotype
Genotype
MGI:5607596
Allelic
Composition		 Lman1tm1c(KOMP)Wtsi/Lman1tm1c(KOMP)Wtsi
Tg(Tek-cre)12Flv/0
Genetic
Background		 involves: C57BL/6 * C57BL/6J * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lman1tm1c(KOMP)Wtsi mutation (0 available); any Lman1 mutation (22 available)
Tg(Tek-cre)12Flv mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal blood homeostasis ( J:213133 )
• mice show a reduction in plasma coagulation factor VIII (FVIII) activity levels
• however plasma coagulation factor V (FV) activity is normal

hematopoietic system
abnormal platelet morphology ( J:213133 )
• modest reduction in platelet FV antigen

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory