Phenotypes Associated with This Genotype

Genotype
MGI:5607954

• Allelic Composition: Plcl1^tm1.1Matk/Plcl1^tm1.1Matk
• Genetic Background: involves: C57BL/6 * FVB

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased incidence of tumors by chemical induction ( J:207384 )

• increase in tumor incidence in a 2-stage (DMBA and TPA) chemical skin carcinogenesis model

mortality/aging

mortality/aging ( J:207384 )

N • Background Sensitivity: increased mortality in a 2-stage (DMBA and TPA) chemical skin carcinogenesis model for mice on an inbred FVB background but not in mice on a mixed C57BL/6 and FVB background

neoplasm

increased incidence of tumors by chemical induction ( J:207384 )

• increase in tumor incidence in a 2-stage (DMBA and TPA) chemical skin carcinogenesis model