Phenotypes for Kras Plcl1 MGI:5607955 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Kras^tm4Tyj/Kras⁺ Plcl1^tm1.1Matk/Plcl1^tm1.1Matk
Genetic Background	involves: 129S4/SvJae * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kras^tm4Tyj mutation (12 available); any Kras mutation (90 available)
Plcl1^tm1.1Matk mutation (0 available); any Plcl1 mutation (54 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

increased tumor incidence ( J:207384 )

• lung tumor incidence in ad-cre infected mice is similar to Kras mutant mice wild-type for Plcl1

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/18/2025 MGI 6.24