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Phenotypes Associated with This Genotype
Genotype
MGI:5608895
Allelic
Composition
Nfkb1M1Btlr/Nfkb1+
Genetic
Background
C57BL/6J-Nfkb1M1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nfkb1M1Btlr mutation (1 available); any Nfkb1 mutation (102 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
• mice bearing this mutation exhibit a reduced T cell dependent IgG response at day 28 following immunization at days 0 and 14 with recombinant Semliki virus- (rSV-) encoded beta-galactosidase; the response of heterozygous mutant mice is intermediate between those of wild-type and homozygous mutant animals.

immune system
• mice bearing this mutation exhibit a reduced T cell dependent IgG response at day 28 following immunization at days 0 and 14 with recombinant Semliki virus- (rSV-) encoded beta-galactosidase; the response of heterozygous mutant mice is intermediate between those of wild-type and homozygous mutant animals.
• mice bearing this mutation exhibit a reduced T cell dependent IgG response at day 28 following immunization at days 0 and 14 with recombinant Semliki virus- (rSV-) encoded beta-galactosidase; the response of heterozygous mutant mice is intermediate between those of wild-type and homozygous mutant animals.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory