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Phenotypes Associated with This Genotype
Genotype
MGI:5632185
Allelic
Composition		 Tnfsf13bm2Btlr/Tnfsf13bm2Btlr
Genetic
Background		 C57BL/6J-Tnfsf13bm2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tnfsf13bm2Btlr mutation (0 available); any Tnfsf13b mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased B cell number ( J:220070 )
• reduced B cell to T cell ratio in peripheral blood.
decreased IgG level ( J:220070 )
• diminished T cell-dependent antibody response to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal).

immune system
decreased B cell number ( J:220070 )
• reduced B cell to T cell ratio in peripheral blood.
decreased IgG level ( J:220070 )
• diminished T cell-dependent antibody response to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal).
impaired humoral immune response ( J:220070 )
• diminished T cell-dependent antibody response to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal).

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory