Phenotypes Associated with This Genotype

Genotype
MGI:5641692

• Allelic Composition: Mysm1^{tm1a(KOMP)Wtsi}/Mysm1^{tm1a(KOMP)Wtsi}
• Genetic Background: C57BL/6-Mysm1^{tm1a(KOMP)Wtsi}
• Cell Lines: EPD0019_1_A05

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

integument

belly spot ( J:209956 , J:232539 )

abnormal hair follicle morphology ( J:209956 )

• abnormalities in the hair follicles

distorted hair follicle pattern ( J:209956 , J:232539 )

• abnormal hair follicle patterning, with hair follicles no longer arranged as staggered rows of triplets (J:209956)

• defects in hair follicle organization and associated structures (J:232539)

abnormal hair cycle ( J:209956 )

• the hair follicle cycle is disturbed, with most hair follicles in telogen

abnormal epidermal layer morphology ( J:209956 )

• abnormalities in the interfollicular epidermis

• within the interfollicular epidermis, the scale pattern is completely disrupted, although regions of scale differentiation lacking the granular layer can still be seen

increased foot pad pigmentation ( J:232539 )

• foot pad hyperpigmentation

decreased tail pigmentation ( J:209956 , J:232539 )

• white tails (J:209956)

limbs/digits/tail

increased foot pad pigmentation ( J:232539 )

• foot pad hyperpigmentation

abnormal hindlimb morphology ( J:232539 )

abnormal tail morphology ( J:209956 )

decreased tail pigmentation ( J:209956 , J:232539 )

• white tails (J:209956)

short tail ( J:232539 )

curly tail ( J:232539 )

kinked tail ( J:209956 )

pigmentation

belly spot ( J:209956 , J:232539 )

increased foot pad pigmentation ( J:232539 )

• foot pad hyperpigmentation

decreased tail pigmentation ( J:209956 , J:232539 )

• white tails (J:209956)