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Phenotypes Associated with This Genotype
Genotype
MGI:5643695
Allelic
Composition		 Foxa2tm2.1(cre/Esr1*)Moon/Foxa2+
Nkx2-5tm1Krc/Nkx2-5tm1Krc
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxa2tm2.1(cre/Esr1*)Moon mutation (1 available); any Foxa2 mutation (31 available)
Nkx2-5tm1Krc mutation (0 available); any Nkx2-5 mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
cardiovascular system phenotype ( J:214093 )
N
• pups from pregnant females treated with tamoxifen at E6.5-7 do not exhibit outflow tract septation or alignment defects

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory