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Phenotypes Associated with This Genotype
Genotype
MGI:5649042
Allelic
Composition
MtdhGt(XB780)Byg/Mtdh+
Tg(Wnt1)1Hev/0
Genetic
Background
FVB.Cg-MtdhGt(XB780)Byg Tg(Wnt1)1Hev
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
MtdhGt(XB780)Byg mutation (0 available); any Mtdh mutation (32 available)
Tg(Wnt1)1Hev mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
neoplasm
• no tumors are detected in 35% of mice at 300 days of age unlike in transgenic mice wild-type for Mtdh
• the number of tumors in mice with tumors is also reduced compared to transgenic mice wild-type for Mtdh
• no tumors are detected in 35% of mice at 300 days of age unlike in transgenic mice wild-type for Mtdh

endocrine/exocrine glands
• no tumors are detected in 35% of mice at 300 days of age unlike in transgenic mice wild-type for Mtdh
• the number of tumors in mice with tumors is also reduced compared to transgenic mice wild-type for Mtdh

integument
• no tumors are detected in 35% of mice at 300 days of age unlike in transgenic mice wild-type for Mtdh
• the number of tumors in mice with tumors is also reduced compared to transgenic mice wild-type for Mtdh


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory