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Phenotypes Associated with This Genotype
Genotype
MGI:5661720
Allelic
Composition		 Celsr1Crsh/Celsr1+
Vangl2Lp/Vangl2+
Genetic
Background		 involves: 101/H * BALB/c * C3H/HeH * CBA * LPT/Le
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Celsr1Crsh mutation (2 available); any Celsr1 mutation (146 available)
Vangl2Lp mutation (2 available); any Vangl2 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
craniorachischisis ( J:216413 )
• 54% of embryos develop craniorachischisis

limbs/digits/tail
curly tail ( J:216413 )
• the mice that do not develop craniorachischisis exhibit a looped tail

nervous system
craniorachischisis ( J:216413 )
• 54% of embryos develop craniorachischisis

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory