Phenotypes Associated with This Genotype

Genotype
MGI:5661738

• Allelic Composition: Celsr1^Crsh/Celsr1^Crsh
• Genetic Background: C3H.Cg-Celsr1^Crsh

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal neural plate morphology ( J:216413 )

• broader neural plate with enlargement of the ventral midline and notochord is seen around the time of neural tube closure initiation

open neural tube ( J:216413 )

• embryos fail to initiate neural tube closure, with 100% open neural tubes at the 9-somite stage

craniorachischisis ( J:216413 )

nervous system

abnormal neural plate morphology ( J:216413 )

• broader neural plate with enlargement of the ventral midline and notochord is seen around the time of neural tube closure initiation

open neural tube ( J:216413 )

• embryos fail to initiate neural tube closure, with 100% open neural tubes at the 9-somite stage

craniorachischisis ( J:216413 )