reproductive system
|
• female mice produced normal litter sizes
|
|
• coiled
|
|
• abnormal anterior acrosome lacking the acrosomal cap
|
|
• when the cumulus mass is intact
|
liver/biliary system
|
• in phytol in CMC-fed mice
|
|
• enlarged peroxisomes in carboxy methyl cellulose (CMC)-fed mice
• decreased number of peroxisomes and an increase in autophagosomes in the liver in phytol in CMC-fed mice
• however, mitochondria appear intact
|
|
• phytol-fed males have increased amount of total fat and triglycerides, indicating onset of fatty liver
|
pale liver
(
J:223054
)
|
• beige in phytol in CMC-fed mice
|
homeostasis/metabolism
|
• in phytol in CMC-fed mice
|
|
• in phytol in CMC-fed mice
|
|
• in phytol in CMC-fed mice
|
|
• several plasmalogen species are reduced compared to in wild-type mice
• however, total levels are normal
|
behavior/neurological
|
• reduced home cage activity in male mice at 34 weeks
|
cellular
|
• coiled
|
|
• abnormal anterior acrosome lacking the acrosomal cap
|
growth/size/body
|
• in phytol in CMC-fed mice
|