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Phenotypes Associated with This Genotype
Genotype
MGI:5695663
Allelic
Composition		 Nox4tm1Syb/Nox4tm1Syb
Genetic
Background		 involves: 129S4/SvJae * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nox4tm1Syb mutation (0 available); any Nox4 mutation (68 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal redox activity ( J:218649 )
• stimulation of mouse aortic smooth muscle cells with Pam3CSK4 results in increased generation of reactive oxygen species (ROS)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/17/2024
MGI 6.24 		The Jackson Laboratory