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Phenotypes Associated with This Genotype
Genotype
MGI:5699726
Allelic
Composition		 Smarca4tm1.2Pcn/Smarca4tm1.2Pcn
Tg(Tek-cre)1Ywa/0
Genetic
Background		 involves: 129S2/SvPas * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smarca4tm1.2Pcn mutation (1 available); any Smarca4 mutation (111 available)
Tg(Tek-cre)1Ywa mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal cardiac outflow tract development ( J:226941 )
• E9.75 embryos exhibit a near complete absence of epithelial-to-mesenchymal transition in the proximal outflow tract
abnormal atrioventricular cushion morphology ( J:226941 )
• E9.75 embryos exhibit a near complete absence of epithelial-to-mesenchymal transition in the atrioventricular canal cushions

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory