Phenotypes Associated with This Genotype

Genotype
MGI:5705236

• Allelic Composition: Irs4^tm1.1Mfw/Y
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:221293 )

♂N • normal leptin levels

♂N • normal fasted glucose levels at 3 months

♂N • normal glucose tolerance

♂N • normal insulin levels

increased circulating glucose level ( J:221293 )

♂ • ad libitum feeding results in insignificantly increased blood glucose

growth/size/body

growth/size/body region phenotype ( J:221293 )

♂N • normal size

mortality/aging

mortality/aging ( J:221293 )

♂N • no embryonic lethality

reproductive system

reproductive system phenotype ( J:221293 )

N • fertile (both sexes)