Phenotypes for Irs2 Irs4 Lepr MGI:5705239 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Irs2^tm2Mfw/Irs2^tm2Mfw Irs4^tm1.1Mfw/Y Lepr^tm3(cre)Mgmj/Lepr⁺
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Irs2^tm2Mfw mutation (0 available); any Irs2 mutation (37 available)
Irs4^tm1.1Mfw mutation (0 available); any Irs4 mutation (6 available)
Lepr^tm3(cre)Mgmj mutation (1 available); any Lepr mutation (125 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:221293 )

N	• blood glucose levels are similar to controls

growth/size/body

growth/size/body region phenotype ( J:221293 )

N	• body weight is essentially similar to homozygous Irs2^tm2Mfw / heterozygous Lepr^tm3(cre)Mgmj male mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24