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Phenotypes Associated with This Genotype
Genotype
MGI:5705287
Allelic
Composition
Anxa8tm1Resc/Anxa8tm1Resc
Tg(Pgk1-cre)1Lni/0
Genetic
Background
involves: 129 * C57BL/6J * BALB/c
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Anxa8tm1Resc mutation (0 available); any Anxa8 mutation (19 available)
Tg(Pgk1-cre)1Lni mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• impaired leukocyte rolling flux and adhesion to inflammatory-activated postcapillary venules
• increased leukocyte rolling velocity

cellular
• impaired leukocyte rolling flux and adhesion to inflammatory-activated postcapillary venules
• increased leukocyte rolling velocity

hematopoietic system
• impaired leukocyte rolling flux and adhesion to inflammatory-activated postcapillary venules
• increased leukocyte rolling velocity


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory