Phenotypes Associated with This Genotype

Genotype
MGI:5706093

• Allelic Composition: Slc25a20^{tm1a(EUCOMM)Wtsi}/Slc25a20^{tm1a(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Slc25a20^{tm1a(EUCOMM)Wtsi}/Wtsi
• Cell Lines: EPD0458_5_E06

Data Sources

IMPC Data for Slc25a20

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

cerebral arteriovenous malformation ( J:239583 )

DMDD

umbilical vein stenosis ( J:239583 )

DMDD

abnormal vitelline vein topology ( J:239583 )

DMDD

ductus venosus stenosis ( J:239583 )

DMDD

jugular vein stenosis ( J:239583 )

DMDD

placenta hemorrhage ( J:261316 )

• hemorrhagic areas/blood pools are seen in the E14.5 placenta

embryo

umbilical vein stenosis ( J:239583 )

DMDD

abnormal vitelline vein topology ( J:239583 )

DMDD

placenta hemorrhage ( J:261316 )

• hemorrhagic areas/blood pools are seen in the E14.5 placenta

abnormal Mullerian duct morphology ( J:239583 )

DMDD

abnormal Wolffian duct topology ( J:239583 )

DMDD

embryo cyst ( J:239583 )

DMDD

endocrine/exocrine glands

multiple persisting craniopharyngeal ducts ( J:239583 )

DMDD

abnormal dorsal pancreas topology ( J:239583 )

DMDD

growth/size/body

embryo cyst ( J:239583 )

DMDD

homeostasis/metabolism

edema ( J:239583 )

DMDD

retropleural edema ( J:239583 )

DMDD

liver/biliary system

herniated liver ( J:239583 )

DMDD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 , J:261316 )

IMPC - WTSI (J:211773)

MGI

• lethality at P14, with viable fetuses at E14.5 (J:261316)

nervous system

cerebral arteriovenous malformation ( J:239583 )

DMDD

multiple persisting craniopharyngeal ducts ( J:239583 )

DMDD

renal/urinary system

double ureter ( J:239583 )

DMDD