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Phenotypes Associated with This Genotype
Genotype
MGI:5706800
Allelic
Composition		 E2f4tm2.1Lees/E2f4tm2.1Lees
E2f5tm1Dli/E2f5tm1Dli
Genetic
Background		 involves: 129S1/Sv * 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
E2f4tm2.1Lees mutation (1 available); any E2f4 mutation (21 available)
E2f5tm1Dli mutation (1 available); any E2f5 mutation (13 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
dilated rete testis ( J:228346 )
• in all mice
abnormal efferent ductules of testis morphology ( J:228346 )
• at 3 weeks, efferent duct epithelium exhibit reduced multiciliated cells compared with control mice

endocrine/exocrine glands
dilated rete testis ( J:228346 )
• in all mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory