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Phenotypes Associated with This Genotype
Genotype
MGI:5752574
Allelic
Composition		 Baxtm2Sjk/Baxtm2Sjk
Scyl2tm1.1Spel/Scyl2tm1.1Spel
Tg(Nes-cre)1Kln/0
Genetic
Background		 involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Baxtm2Sjk mutation (1 available); any Bax mutation (24 available)
Scyl2tm1.1Spel mutation (0 available); any Scyl2 mutation (37 available)
Tg(Nes-cre)1Kln mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
preweaning lethality, incomplete penetrance ( J:225808 )
• fewer than expected mice are present at weaning

growth/size/body
decreased body size ( J:225808 )

behavior/neurological
behavior/neurological phenotype ( J:225808 )
N
• mice do not exhibit limb clasping as in Scyl2tm1.1Spel/Scyl2tm1.1Spel Tg(Nes-cre)1Kln mice

nervous system
nervous system phenotype ( J:225808 )
N
• mice exhibit nor brain abnormalities unlike in Scyl2tm1.1Spel/Scyl2tm1.1Spel Tg(Nes-cre)1Kln mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory