Phenotypes Associated with This Genotype

Genotype
MGI:5752575

• Allelic Composition: Scyl2^tm1.2Spel/Scyl2^tm1.2Spel
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, incomplete penetrance ( J:225808 )

• most mice die within 24 hours of birth

• however, mice that survive are present at weaning

behavior/neurological

abnormal behavior ( J:225808 )

• sensory-motor deficits and abnormal behaviors in mice that survive beyond the neonatal period

absent gastric milk in neonates ( J:225808 )

limb grasping ( J:225808 )

• in mice that survive beyond the neonatal period

growth/size/body

postnatal growth retardation ( J:225808 )

• in mice that survive beyond the neonatal period

craniofacial

craniofacial phenotype ( J:225808 )

N • mice exhibit normal craniofacial morphology