Phenotypes Associated with This Genotype

Genotype
MGI:5755409

• Allelic Composition: Emilin1^tm1Gmb/Emilin1^tm1Gmb; Emilin2^tm1.2Jhp/Emilin2^tm1.2Jhp
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

abnormal blood coagulation ( J:226863 )

• mice exhibit delayed clot retraction compared with wild-type mice as in Emilin2^tm1.2Jhp homozygotes

• however, mice exhibit normal clotting time

decreased platelet aggregation ( J:226863 )

• in ADP platelet-rich plasma, with collagen stimulated platelets in platelet-rich plasma and with washed platelets stimulated with thrombin

• of ADP stimulated platelets

hematopoietic system

decreased platelet aggregation ( J:226863 )

• in ADP platelet-rich plasma, with collagen stimulated platelets in platelet-rich plasma and with washed platelets stimulated with thrombin

• of ADP stimulated platelets