Phenotypes Associated with This Genotype

Genotype
MGI:5781683

• Allelic Composition: Nfkb1^{tm1a(KOMP)Wtsi}/Nfkb1^{tm1a(KOMP)Wtsi}
• Genetic Background: B6JTyr;B6N-Nfkb1^{tm1a(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0033_4_D01

Data Sources

IMPC Data for Nfkb1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased lean body mass ( J:175295 )

♂

IMPC - WTSI

hematopoietic system

decreased mean corpuscular hemoglobin concentration ( J:175295 )

♂

IMPC - WTSI

increased leukocyte cell number ( J:165965 , J:175295 )

IMPC - WTSI (J:165965)

IMPC - WTSI (J:175295)

homeostasis/metabolism

increased circulating free fatty acids level ( J:175295 )

IMPC - WTSI

decreased circulating sodium level ( J:165965 )

♂

IMPC - WTSI

increased circulating alkaline phosphatase level ( J:165965 )

♀

IMPC - WTSI

decreased circulating amylase level ( J:175295 )

IMPC - WTSI

immune system

increased leukocyte cell number ( J:165965 , J:175295 )

IMPC - WTSI (J:165965)

IMPC - WTSI (J:175295)

behavior/neurological

decreased thermal nociceptive threshold ( J:165965 )

♀

IMPC - WTSI

increased thermal nociceptive threshold ( J:165965 )

♂

IMPC - WTSI

integument

abnormal skin condition ( J:165965 )

♀

IMPC - WTSI

vision/eye

abnormal cornea morphology ( J:165965 )

♀

IMPC - WTSI