Phenotypes Associated with This Genotype

Genotype
MGI:5790971

• Allelic Composition: Nfkb1^{tm1a(KOMP)Wtsi}/Nfkb1^{tm1a(KOMP)Wtsi}
• Genetic Background: involves: C57BL/6 * C57BL/6N
• Cell Lines: EPD0033_4_D01

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

decreased NK cell number ( J:213427 )

decreased regulatory T cell number ( J:213427 )

increased leukocyte cell number ( J:213427 )

decreased IgA level ( J:213427 )

decreased IgG1 level ( J:213427 )

homeostasis/metabolism

increased circulating alkaline phosphatase level ( J:213427 )

decreased respiratory quotient ( J:213427 )

immune system

decreased NK cell number ( J:213427 )

decreased regulatory T cell number ( J:213427 )

increased leukocyte cell number ( J:213427 )

decreased IgA level ( J:213427 )

decreased IgG1 level ( J:213427 )

lymphoid hyperplasia ( J:213427 )

increased susceptibility to bacterial infection ( J:213427 )