Phenotypes Associated with This Genotype

Genotype
MGI:5790994

• Allelic Composition: Prmt3^{tm1a(EUCOMM)Wtsi}/Prmt3^{tm1a(EUCOMM)Wtsi}
• Genetic Background: involves: C57BL/6 * C57BL/6N
• Cell Lines: EPD0070_5_D05

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased body weight ( J:213427 )

decreased body length ( J:213427 )

hematopoietic system

increased T cell number ( J:213427 )

increased CD4-positive, alpha-beta T cell number ( J:213427 )

increased CD8-positive, alpha-beta T cell number ( J:213427 )

homeostasis/metabolism

decreased respiratory quotient ( J:213427 )

immune system

increased T cell number ( J:213427 )

increased CD4-positive, alpha-beta T cell number ( J:213427 )

increased CD8-positive, alpha-beta T cell number ( J:213427 )

increased incidence of corneal inflammation ( J:213427 )

• keratitis

mortality/aging

lethality, incomplete penetrance ( J:213427 )

decreased survivor rate ( J:213427 )

postnatal lethality, incomplete penetrance ( J:213427 )

nervous system

hydrocephaly ( J:213427 )

skeleton

decreased bone mineral content ( J:213427 )

decreased bone mineral density ( J:213427 )

vision/eye

increased incidence of corneal inflammation ( J:213427 )

• keratitis

abnormal cornea morphology ( J:213427 )

cornea opacity ( J:213427 )

cataract ( J:213427 )

narrow eye opening ( J:213427 )