Phenotypes for Gt(ROSA)26Sor Tg(Cd4-cre)1Cwi Traf3ip3 MGI:5795855 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Gt(ROSA)26Sor^{tm8(Map2k1*,EGFP)Rsky}/Gt(ROSA)26Sor⁺ Tg(Cd4-cre)1Cwi/0 Traf3ip3^{tm1c(KOMP)Wtsi}/Traf3ip3^{tm1c(KOMP)Wtsi}
Genetic Background	involves: C57BL/6 * C57BL/6N * DBA/2
Cell Lines	EPD0093_2_B04

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sor^{tm8(Map2k1*,EGFP)Rsky} mutation (1 available); any Gt(ROSA)26Sor mutation (1027 available)
Tg(Cd4-cre)1Cwi mutation (10 available)
Traf3ip3^{tm1c(KOMP)Wtsi} mutation (0 available); any Traf3ip3 mutation (34 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

immune system phenotype ( J:226431 )

N	• constitutively active Map2k1(MEK) rescues thymocyte development restoring single positive thymocyte and splenic T cell populations

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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